Stage 2 grade 3 carcinosarcoma is an aggressive form of endometrial cancer, so treatment is typically more intensive. The good news is that stage 2 is still considered localized, meaning it hasn't spread beyond the uterus and nearby tissues.
Treatment generally involves a combination of approaches:
- Surgery first — Show Full Answer
Stage 2 grade 3 carcinosarcoma is an aggressive form of endometrial cancer, so treatment is typically more intensive. The good news is that stage 2 is still considered localized, meaning it hasn't spread beyond the uterus and nearby tissues.
Treatment generally involves a combination of approaches:
- Surgery first — usually a radical hysterectomy, which removes the uterus, cervix, upper vagina, and nearby lymph nodes
- Radiation therapy after surgery — either external beam radiation (EBRT) or internal radiation (brachytherapy), or both
- Chemotherapy — commonly a combination of carboplatin and paclitaxel, given through an IV after surgery Because carcinosarcoma is considered a high-grade, aggressive cancer, your oncologist may also discuss immunotherapy options depending on specific markers found in your tumor cells, such as dMMR or MSI-H status.
It's really important to work closely with your cancer care team to build a personalized plan. Asking about clinical trials is also worth considering, as new treatments are always being explored.
June 3
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