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A MyEndometrialCancerTeam Member asked a question in Side Effects group 💭

At my first infusion therapy the Nurse wanted me to only ice during the Keytruda infusion. My second infusion Nurse had the same advice. I told her the literature they gave me on Placitaxol, Carboplatin, and Keytruda all listed neuropathy as a side effect. I will ask for more details next time to try and reason out their odd recommendation. Has anyone else been told not to ice for the whole infusion period?

April 26, 2025
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Answer Summary

Members dove deep into the question of when to ice during chemo infusions, with many sharing confusion over conflicting nurse advice about... Read more

Members dove deep into the question of when to ice during chemo infusions, with many sharing confusion over conflicting nurse advice about which drugs (Taxol, Carboplatin, or Keytruda) actually require icing. Several members shared detailed strategies including using cycling ice chests for hands and feet, compression socks, B6 supplements, and acupuncture, with many reporting success in reducing neuropathy symptoms. A recurring theme was the importance of self-advocacy, asking doctors and nurses for clear reasoning, and researching neuropathy percentages to make informed personal decisions.

A MyEndometrialCancerTeam Member

You can bring your own ice and bags or buy the icing gloves and socks. There are many options on Amazon.

April 17
A MyEndometrialCancerTeam Member

I dropped the Paclitaxel by 20% on round 4 of 6, didn’t help, so dropped Paclitaxel entirely from round 5 ~ Carboplatin only. Decided to eliminate round 6 altogether. In my discussion with my oncologist, she said the Paclitaxel was the major cause of neuropathy. So here I am 9 1/2 years later and will be receiving the exact same 6 rounds, same chemicals except adding Keytruda to the mix which will continue every 3 weeks for 2 years OR until my body cries “uncle” or the cancer overcomes me. Having said that, I will be prepared with Plan A and Plan B, but taking each day as it comes and having deep discussions with my doctors.

March 23
A MyEndometrialCancerTeam Member

I had severe bone and muscle pain… I tried ice on hands and legs but the neuro pain was in legs… I didn’t find ice to help during chemo infusion… I found walking more effective even at 2am! I did ask my Oncologist for an Rx of Soma which helped tremendously… I had an injury with surgery to my cervical region and soma helped with bone and nerve pain back then…

May 9, 2025
A MyEndometrialCancerTeam Member

I first was given steroids and iv Benadryl to help with the side effects of the Taxol. Then I iced my feet and hands and was given the Taxol. I did not take breaks except to change the bags of ice when they melted. I wore thin socks on my feet and them put the hospital socks over the ice bags and my feet. For my hands I used thin cheap cotton gloves with the finger tips cut off and then put my hand in the bags of ice. The bags that Memorial Sloan Kettering gives you have pocket for your hands so there is plastic between your hands and the ice. When the Taxol was done I stopped icing. I then received the Carboplatin. Once that was done I was given 500 mg of Dostarlimab. I had very mild neuropathy if at all. I did have bone pain that started about 2 days after chemo at night, and by the 5th round it was very uncomfortable. But the pain was only at night and only lasted for 2-3 nights. My doctors worked to find the right medication to help me sleep and dull the pain. But is was only at night and only for 2-3 nights on the weeks I received Chemo.

May 2, 2025
A MyEndometrialCancerTeam Member

Thanks for looking up the statistics on neuropathy. Wonder what the source of the misinformation is! I'll let you know what my Dr says after my next appointment 3 wks from now. I was dismayed when they did not recommend icing as a preventative and I had to ask about it. There must be some controversy connected with it is my only guess.

April 28, 2025

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