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My diagnosis is 1-1b
Had three brachytherapy treatments and have no symptoms but a recent UTI . When I had my last blood drawn. Care team suggested having a cat scan with contrast. Signatara consultant said my reading is positive but under the analytical range. They said most likely nothing would show up with that reading on the cat scan. I have had a recent mammogram, colon test, and chest xray. I requested a CA127 test but they do not think I should have that.

June 10, 2025
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A MyEndometrialCancerTeam Member

Hi, were you able to get the tests you wanted? How are you doing? I scheduled a colonoscopy and a breast MRI after my cancer diagnosis. I just had my Signatera test, so I'm not sure what to expect.

September 23, 2025
myEndometrialCancerTeam

Your care team's approach to monitoring with multiple screening methods is thorough. While your Signatera readings show a slight increase, they remain below the analytical range, which explains why your consultant believes a CT scan may not show anything at these levels.

Regarding tumor markers, CA-125 (not CA-127) is the Show Full Answer

Your care team's approach to monitoring with multiple screening methods is thorough. While your Signatera readings show a slight increase, they remain below the analytical range, which explains why your consultant believes a CT scan may not show anything at these levels.

Regarding tumor markers, CA-125 (not CA-127) is the blood test typically used for endometrial cancer monitoring. This test can help indicate if cancer has spread outside the uterus, though it's not used for initial diagnosis. It's worth noting that some symptoms you mentioned, like UTI, can be related to brachytherapy side effects. Common side effects can include:
- Pain while urinating
- Blood in urine
- Vaginal irritation
- Bladder irritation (radiation cystitis)

Continue to communicate any new or changing symptoms with your care team, as they can help manage these side effects while monitoring your condition.

June 10, 2025

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