Hi Coleen. I hope they can come up with a more accurate marker. I have had 3 recurrences. 2 were in the vaginal vault and the 3rd one was in my mediastinal lymph nodes. The only time my CA 125 was above normal was when I had the 3 rd recurrence. Have a blessed day
October 14, 2025
A cancer antigen is a substance that cancer cells can release into the bloodstream. For endometrial cancer specifically, some cancer cells release Cancer Antigen 125 (CA-125) into the blood.
While CA-125 blood tests aren't used to diagnose endometrial cancer, elevated levels can indicate that cancer has spread beyond the Show Full Answer
A cancer antigen is a substance that cancer cells can release into the bloodstream. For endometrial cancer specifically, some cancer cells release Cancer Antigen 125 (CA-125) into the blood.
While CA-125 blood tests aren't used to diagnose endometrial cancer, elevated levels can indicate that cancer has spread beyond the uterus. Doctors may monitor CA-125 levels periodically during treatment - levels typically should decrease after surgery or during effective treatment. It's important to note that CA-125 is just one of several markers doctors may test for. Your healthcare team might also check for other biomarkers, including hormone receptors and genetic mutations, which can help determine the most effective treatment options for your specific case.
October 13, 2025