Has anyone else experienced endometrial cancer that spread to the colon and had surgery?
Endometrial cancer spreading to the colon is indeed rare. While the search results don't include specific member experiences with colon surgery for metastatic endometrial cancer, the information confirms that spread to the rectum and Show Full Answer
Has anyone else experienced endometrial cancer that spread to the colon and had surgery?
Endometrial cancer spreading to the colon is indeed rare. While the search results don't include specific member experiences with colon surgery for metastatic endometrial cancer, the information confirms that spread to the rectum and bowel area is uncommon.
When endometrial cancer does spread to the bowel, symptoms can include constipation, diarrhea, and blood in stool. Some reports note that most people with cancer spread to the rectum also have endometriosis, where uterine tissues grow outside the uterus.
Getting a second opinion is a wise step, especially given your unique situation. Your oncologist's concerns about quality of life after colon resection surgery are valid considerations, particularly regarding the potential need for an ostomy bag.
Since your cancer is HER2 positive and responded initially to targeted therapy, switching to Enhertu (which also targets HER2) could be a reasonable option to explore. A second opinion can help you weigh the risks and benefits of surgery versus continuing with targeted medication.
Given how rare this specific metastasis pattern is, connecting with others who've faced similar decisions might be challenging, but your medical team's expertise with your individual case will be most valuable in making this decision.
December 19, 2025