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April 25
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myEndometrialCancerTeam

What a challenging situation for your family member β€” having both Type I (endometrioid) and Type II (serous) endometrial cancer means her treatment plan will likely be more complex, but there are good options available.

Treatment will depend on several key factors, including:

- The stage and grade of the cancer
- How far Show Full Answer

What a challenging situation for your family member β€” having both Type I (endometrioid) and Type II (serous) endometrial cancer means her treatment plan will likely be more complex, but there are good options available.

Treatment will depend on several key factors, including:

- The stage and grade of the cancer
- How far it has spread
- Her overall health
- Biomarker testing results (such as dMMR and MSI genetic markers)
- Hormone receptor status Because Type II (serous) endometrial cancer tends to be more aggressive, her care team will likely recommend a combination of treatments. Here's what is commonly used:

- Surgery β€” A hysterectomy (removal of the uterus, ovaries, and fallopian tubes) is typically the first step
- Chemotherapy β€” Usually carboplatin and paclitaxel together
- Radiation therapy β€” Either external beam radiation or brachytherapy (internal radiation)
- Immunotherapy β€” Such as pembrolizumab (Keytruda) or dostarlimab (Jemperli), especially if certain biomarkers are present
- Hormone therapy β€” May be considered depending on hormone receptor status
- Targeted therapy β€” Targets specific mutations in cancer cells

It's also worth asking her oncologist about clinical trials, which may give access to newer treatments not yet widely available. The most important next step is for her gynecologic oncologist to review all her test results and build a personalized treatment plan. Every case is unique, and her team will tailor the approach specifically to her situation. Encourage her to ask questions and discuss any concerns β€” she deserves to feel informed and supported every step of the way. πŸ’™

April 25

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San Antonio, TX

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