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Fairfax, VA
July 18
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Grade 3 endometrial cancer is considered high-grade, meaning the cancer cells look very different from normal, healthy cells. These cells are more aggressive, tend to grow faster, and are more likely to spread than lower-grade cancers. To understand grading, it helps to know how the scale works. Endometrial cancer is graded Show Full Answer

Grade 3 endometrial cancer is considered high-grade, meaning the cancer cells look very different from normal, healthy cells. These cells are more aggressive, tend to grow faster, and are more likely to spread than lower-grade cancers. To understand grading, it helps to know how the scale works. Endometrial cancer is graded on a scale of 1 to 3:

- Grade 1 – Cells look mostly normal, slow-growing, and less likely to spread
- Grade 2 – Cells look somewhat abnormal and are moderately aggressive
- Grade 3 – Cells look very abnormal, are fast-growing, and more likely to spread In terms of survival, a study of 276 people with endometrial cancer found three-year overall survival rates were:

- Grade 1 – 95.6%
- Grade 2 – 82.1%
- Grade 3 – 61.9%

While these numbers can feel daunting, it's important to remember that survival rates are based on large groups of people and don't predict any one individual's outcome. Treatment advances continue to improve outcomes, so it's always worth having an open conversation with your care team about what these numbers mean for your specific situation.

July 18

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