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Real members of MyEndometrialCancerTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
2 days ago
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Nine years in remission is a remarkable milestone β€” that's genuinely worth celebrating! πŸŽ‰

The question of whether to continue letrozole (a hormone therapy) beyond 10 years is a very individualized decision, especially with a history of recurrent metastatic endometrial cancer.

There are several key factors your oncologist Show Full Answer

Nine years in remission is a remarkable milestone β€” that's genuinely worth celebrating! πŸŽ‰

The question of whether to continue letrozole (a hormone therapy) beyond 10 years is a very individualized decision, especially with a history of recurrent metastatic endometrial cancer.

There are several key factors your oncologist will weigh:

- Your current biomarkers β€” such as mismatch repair deficiency (dMMR) or microsatellite instability (MSI), which can guide treatment decisions
- Your overall health and how well you've tolerated letrozole
- The risk of recurrence versus the long-term side effects of continuing hormone therapy
- New treatment options that may now be available, including immunotherapy or targeted therapies It's really important to have an open, honest conversation with your oncologist before making any changes. They can review your full history and help determine whether continuing, stopping, or switching therapies makes the most sense for your specific situation.

Asking about clinical trials is also worth considering, as newer treatments continue to emerge for endometrial cancer.

2 days ago

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