Does a drop in CA-125 from 350 to 30 with chemo mean tumors are smaller?
That's a significant drop in your CA-125 level, which is definitely encouraging! A decreasing CA-125 level typically suggests that your treatment is working.
CA-125 is a protein that some endometrial cancers release into the bloodstream. When levels Show Full Answer
Does a drop in CA-125 from 350 to 30 with chemo mean tumors are smaller?
That's a significant drop in your CA-125 level, which is definitely encouraging! A decreasing CA-125 level typically suggests that your treatment is working.
CA-125 is a protein that some endometrial cancers release into the bloodstream. When levels drop during treatment, it usually indicates that the cancer is responding positively to chemotherapy.
However, CA-125 levels alone don't directly measure tumor size. To know for certain if your tumors have shrunk, imaging tests are needed, such as:
* CT scans
* MRI scans
* PET scans
These imaging tests can actually visualize the tumors and show whether they've decreased in size.
Your cancer care team will likely use both your CA-125 levels and imaging tests together to get the complete picture of how well your treatment is working. The drop in CA-125 is a positive sign, but imaging provides the definitive answer about tumor size.
Make sure to discuss these results with your oncologist, who can explain what this means for your specific situation and next steps in your treatment plan.
December 17, 2025
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