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Chemo cancelled due to recurrence on vaginal cuff after four infusions.. PET scan showed metastases to bones, lymph nodes and lungs
Started keytruda three weeks ago and had second one yesterday
Lenvima cancelled after one day bc radiation was going to be administered to alleviate hip pain to lesion on bone.
I was told radiation to tumor would help with the bleeding but doctors recommended trying immunotherapy first.
When I reported the blood clots this afternoon, oncologist said radiation… read more

February 20
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A MyEndometrialCancerTeam Member

Martha, I did not pass any blood clots after my infusion of keytruda.

March 1
myEndometrialCancerTeam

Are you experiencing blood clots after starting Keytruda and Lenvima?

Passing blood clots after starting immunotherapy can happen, especially when you have recurrence on the vaginal cuff. Vaginal bleeding is a known concern with endometrial cancer, particularly when there's tumor involvement in that area.

Your Show Full Answer

Are you experiencing blood clots after starting Keytruda and Lenvima?

Passing blood clots after starting immunotherapy can happen, especially when you have recurrence on the vaginal cuff. Vaginal bleeding is a known concern with endometrial cancer, particularly when there's tumor involvement in that area.

Your oncologist's recommendation to monitor the bleeding over the weekend and proceed with radiation makes sense. Radiation therapy can help control bleeding from tumors, including those on the vaginal cuff or bone lesions. The radiation should target the tumor causing the bleeding while also helping with your hip pain from the bone lesion.

Important things to watch for:

* Heavy bleeding that soaks through pads quickly
* Passing large clots (bigger than a quarter)
* Dizziness or feeling faint
* Increased pelvic pain

If any of these occur, contact your oncology team right away rather than waiting until your next appointment. While monitoring over the weekend is reasonable, don't hesitate to reach out if symptoms worsen.

The combination of Keytruda and lenvatinib (Lenvima) is used for advanced endometrial cancer that has spread, so your treatment plan aligns with standard approaches for metastatic disease.

February 20

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