Planning a total hysterectomy for stage 3A endometrial cancer in May 2026 — and wondering about skipping chemo/radiation in favor of immunotherapy — is a really important question to explore carefully with your oncologist.
For stage 3A endometrial cancer, surgery is typically the starting point, but it's rarely used alone Show Full Answer
Planning a total hysterectomy for stage 3A endometrial cancer in May 2026 — and wondering about skipping chemo/radiation in favor of immunotherapy — is a really important question to explore carefully with your oncologist.
For stage 3A endometrial cancer, surgery is typically the starting point, but it's rarely used alone. Here's what treatment usually looks like at this stage:
- Surgery removes the uterus, ovaries, fallopian tubes, and often nearby lymph nodes
- Radiation therapy is commonly recommended after surgery to target remaining cancer cells
- Chemotherapy is often combined with radiation for stage 3 to improve outcomes
- Immunotherapy may be recommended, particularly if your cancer has certain genetic markers (like mismatch repair deficiency) Postponing or skipping chemotherapy and radiation in favor of immunotherapy alone carries real risks at stage 3A. Combining treatments has shown better survival outcomes than single-treatment approaches for advanced stages.
Immunotherapy has shown promising results, especially for certain tumor types, but it's generally used alongside other treatments rather than as a replacement.
The most important step is having a detailed conversation with your oncologist about your tumor's specific characteristics — this will determine which combination of treatments gives the best chance of success for your individual situation.
July 10
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