myEndometrialCancerTeam

It's great that you're doing your research — knowing what to expect can make a real difference. Lenvatinib (Lenvima) combined with pembrolizumab (Keytruda) is an FDA-approved treatment option for advanced endometrial cancer, particularly when surgery or radiation isn't an option.

Here are the common side effects to be aware Show Full Answer

It's great that you're doing your research — knowing what to expect can make a real difference. Lenvatinib (Lenvima) combined with pembrolizumab (Keytruda) is an FDA-approved treatment option for advanced endometrial cancer, particularly when surgery or radiation isn't an option.

Here are the common side effects to be aware of:

- High blood pressure
- Fatigue
- Diarrhea
- Joint and muscle pain
- Decreased appetite
- Nausea or vomiting
- Mouth sores
- Weight loss
- Headache
- Skin rash, redness, itching, or peeling (especially hands and feet)
- Hoarseness
- Constipation
- Urinary tract infections There are also some rare but serious side effects worth discussing with your care team:

- Heart problems or irregular heart rhythm
- Blood clots in arteries
- Liver or kidney damage
- Severe diarrhea
- Abnormal connections between organs (fistula)
- Holes in the stomach or intestines
- Low calcium levels
- Jaw bone damage
- Bleeding events
- Thyroid problems
- Impaired wound healing

Your oncology team will monitor you closely for these. Always report any new or worsening symptoms promptly — don't try to tough it out alone!

 AI-generated responses are not a substitute for medical advice. These services are not intended to diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.

Treatments

Lenvima

Keytruda Qlex