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Real members of MyEndometrialCancerTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
October 6
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myEndometrialCancerTeam

Has anyone experienced endometrial cancer returning to the peritoneal cavity after 3 years, while on Everolimus and Letrozole?

While direct experiences from others aren't available here, some MyEndometrialCancerTeam members have shared that recurrence can happen even after the typical 3-year window, though it's less common Show Full Answer

Has anyone experienced endometrial cancer returning to the peritoneal cavity after 3 years, while on Everolimus and Letrozole?

While direct experiences from others aren't available here, some MyEndometrialCancerTeam members have shared that recurrence can happen even after the typical 3-year window, though it's less common. Most recurrences do tend to happen within the first 3 years after treatment. When endometrial cancer returns, several factors influence where and how it comes back, including:

- The original stage of the cancer
- Tumor grade and size
- How deeply the cancer invaded the uterine muscle wall
- The type of endometrial cancer (Type 1 vs. Type 2)

The combination of Everolimus and Letrozole is a recognized treatment approach for recurrent endometrial cancer, so it's great that you're already working with your oncology team on a plan. It's worth having an open conversation with your oncologist about whether additional treatment options — such as immunotherapy, targeted therapy, or clinical trials — might complement your current regimen. New treatments are continuing to improve outcomes for people in similar situations.

Connecting with others on MyEndometrialCancerTeam who've had similar experiences can also be a great source of support and shared insight. 💙

October 6

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