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October 17
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A MyEndometrialCancerTeam Member

Hi Melanie. Sorry you have this. Most likely the Taxol chemo is the culprit. I take an NSAID for pain. I only have neuropathy in my toes, so I’m careful what shoes I wear . There are some shoes now that are designed for people with neuropathy. I did go to a podiatrist and he helped . Talk to your doctor if medication might help. Gabapentin helps some. Best of care to you. Oh. Heat and warmth help my hands but I have arthritis.

October 18
A MyEndometrialCancerTeam Member

Hi, I'm Lisa...I was diagnosed with Endometrial Adenocarcinoma in October 2023...I had 5 of the 6 rounds of Paclitaxol and 6 of the 6 rounds of Carboplatin...My foot neuropathy felt weird. It appeared after the 4th chemotherapy infusion...My oncologist prescribed Gabapentin. I'm 2 years post treatment and under medical surveillance for Endometrial Adenocarcinoma FIGO 1, but it was Stage 3, because thd cancer spread to my para-aortic and pelvic lymph nodes. Endured 6 chemotherapy infusions of Paclitaxol and Carboplatin (each round was 3 weeks from the last round), 7 rounds of 25 ordered rounds of Grey45 radiation. I could not tolerate radiation. But my oncologist said I "handled chemotherapy like a champ"....I never vomited because I ate small, frequent meals..I did feel nauseous but Ondasetron helped with the nausea symptoms...Because of the radiation, my quality of life was nil because of constant diarrhea. I STOPPED radiation. QoL improved. I'm almost 3 years post treatment. My CA-125 blood tests are within normal limits. CAT scans are looking great. And my physical internal pelvic exam to monitor the vaginal cuff is checked...My para-aortic and pelvic lymph nodes shrunk back down to normal size. I endured a laparoscopic robotic-assisted radical hysterectomy with the "DaVinci Robotic System" in between chemotherapy rounds 3 and 4....There has to be a 3 week interval in between each chemotherapy infusion..I'm under medical surveillance right now. I see my oncologist every 3 months. So the neuropathy may heal in time and physical symptoms may subside. It takes several months, sometimes years to regenerate nerves and in my case, it seems like the neuropathy is improving...Blessings to you!

7 days ago
myEndometrialCancerTeam

What can be done to manage neuropathy pain in the feet and hands during endometrial cancer treatment?

Neuropathy (nerve pain) in the hands and feet is a common side effect of some endometrial cancer treatments. There are several approaches that may help manage this discomfort.

Here are some options worth discussing with your Show Full Answer

What can be done to manage neuropathy pain in the feet and hands during endometrial cancer treatment?

Neuropathy (nerve pain) in the hands and feet is a common side effect of some endometrial cancer treatments. There are several approaches that may help manage this discomfort.

Here are some options worth discussing with your doctor:

Medications:
- Over-the-counter options like ibuprofen or acetaminophen for mild pain
- Prescription medications like gabapentin, which targets nerve pain specifically
- Topical treatments like lidocaine cream

Complementary Therapies:
- Acupuncture
- Massage therapy
- Certain vitamin supplements (always check with your doctor first)

Physical Approaches:
- Alternating warm compresses and ice packs — heat can ease muscle tension, while cold can reduce nerve pain and inflammation
- Gentle movement like walking, yoga, or tai chi
- Physical therapy

Important cautions:
- Always consult your healthcare provider before starting any new supplement or device
- Some medications carry serious side effects with long-term use
- If you're receiving radiation therapy, heat therapy may need to be avoided

Your care team can help tailor a pain management plan that's right for your specific situation. Don't hesitate to be open with them about how the pain is affecting you — they can adjust your plan as needed.

October 17

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