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A MyEndometrialCancerTeam Member asked a question 💭
Munich, DE
October 24
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A MyEndometrialCancerTeam Member

Hi, I'm Lisa...I was diagnosed with Endometrial Adenocarcinoma in October 2023...I had 5 of the 6 rounds of Paclitaxol and 6 of the 6 rounds of Carboplatin...My foot neuropathy felt weird. It appeared after the 4th chemotherapy infusion...My oncologist prescribed Gabapentin. I'm 2 years post treatment and under medical surveillance for Endometrial Adenocarcinoma FIGO 1, but it was Stage 3, because thd cancer spread to my para-aortic and pelvic lymph nodes. Endured 6 chemotherapy infusions of Paclitaxol and Carboplatin (each round was 3 weeks from the last round), 7 rounds of 25 ordered rounds of Grey45 radiation. I could not tolerate radiation. But my oncologist said I "handled chemotherapy like a champ"....I never vomited because I ate small, frequent meals..I did feel nauseous but Ondasetron helped with the nausea symptoms...Because of the radiation, my quality of life was nil because of constant diarrhea. I STOPPED radiation. QoL improved. I'm almost 3 years post treatment. My CA-125 blood tests are within normal limits. CAT scans are looking great. And my physical internal pelvic exam to monitor the vaginal cuff is checked...My para-aortic and pelvic lymph nodes shrunk back down to normal size. I endured a laparoscopic robotic-assisted radical hysterectomy with the "DaVinci Robotic System" in between chemotherapy rounds 3 and 4....There has to be a 3 week interval in between each chemotherapy infusion..I'm under medical surveillance right now. I see my oncologist every 3 months. So the neuropathy may heal in time and physical symptoms may subside. It takes several months, sometimes years to regenerate nerves and in my case, it seems like the neuropathy is improving...I hope you are doing alright....Blessings to you!

7 days ago
myEndometrialCancerTeam

Paclitaxel can cause nerve pain (neuropathy), muscle and joint pain, and general discomfort. Here are some approaches that may help manage it:

Medications
- Over-the-counter options like ibuprofen or acetaminophen for mild pain
- Gabapentin or certain antidepressants for nerve pain
- Stronger prescription options if pain is Show Full Answer

Paclitaxel can cause nerve pain (neuropathy), muscle and joint pain, and general discomfort. Here are some approaches that may help manage it:

Medications
- Over-the-counter options like ibuprofen or acetaminophen for mild pain
- Gabapentin or certain antidepressants for nerve pain
- Stronger prescription options if pain is more severe — always discuss with your doctor first

Physical approaches
- Cold therapy (ice packs) to help reduce nerve pain and inflammation
- Gentle movement like walking, yoga, or tai chi to release natural pain-relieving endorphins
- Physical therapy

Complementary options
- Acupuncture or massage may offer some relief
- Breathing exercises and relaxation techniques

Diet
- Avoiding heavily processed foods and hydrogenated oils may help reduce inflammation

Always check with your care team before starting or stopping anything. They can also connect you with a palliative care specialist who can help manage symptoms more holistically — addressing physical, emotional, and mental well-being alongside your treatment.

You're not alone in navigating this, and finding the right combination of strategies can make a real difference.

October 24

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