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Has anyone have Mets in their lung and a rapidly growing subcarinal lymph node about 3 inches? On radiation now. Have serous carcinoma.

A MyEndometrialCancerTeam Member asked a question 💭

Since 2022 stage 2, now stage 4 with Mets discovered July 2025. My oncologist didn't order any scans for a year and a half prior to July which I insisted on. Have done the chemo which quit working. Had radiation in pelvic area. On Lenvima and infusion therapy until June in which I had a high blood pressure event so quit that.

October 26
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myEndometrialCancerTeam

What a journey you've been through — and it's clear you've been your own best advocate by pushing for those scans. That matters enormously.

Other MyEndometrialCancerTeam members have shared experiences with lung metastases and serous carcinoma progressing to stage 4, so you're not alone in navigating this difficult path.

Show Full Answer

What a journey you've been through — and it's clear you've been your own best advocate by pushing for those scans. That matters enormously.

Other MyEndometrialCancerTeam members have shared experiences with lung metastases and serous carcinoma progressing to stage 4, so you're not alone in navigating this difficult path.

Serous carcinoma is known to be a more aggressive, fast-growing type of endometrial cancer, which can explain the rapid progression and spread to lymph nodes and lungs. For stage 4 with lung metastases, treatment options your oncologist may consider include:

- Radiation — which you're currently receiving, and can help target specific tumors
- Immunotherapy — newer approvals have shown promise for advanced endometrial cancer
- Hormone therapy — another systemic option
- Alternative chemotherapy combinations — if prior chemo stopped working, different drug combinations may be explored

Given the high blood pressure event that stopped your infusion therapy, it's really important to keep your care team updated on all side effects so they can adjust your plan safely. It may be worth asking your oncologist specifically about immunotherapy options, as several have recently been approved for advanced endometrial cancer and may be a viable next step.

A second opinion from a gynecologic oncology specialist at a major cancer center could also be valuable given how quickly things have progressed.

October 26

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Correction: Cancer reoccurrence spread to chest not heart !

A MyEndometrialCancerTeam Member asked a question 💭
September 26 (edited)

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