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Real members of MyEndometrialCancerTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyEndometrialCancerTeam Member asked a question 💭
Los Angeles, CA

(I'm on Taxol, Carboplatin ROUND 1, DAY 11). Rash started 3 days ago and it's getting progressively worse. Moisturizing with a fragrance-free lotion, but wondering if I can take anything - Benadryl? I'M SO UNCOMFORTABLE!! What helped you? I'll try anything for some relief! :)

July 6, 2025
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A MyEndometrialCancerTeam Member

Thanks and I just spoke to the doctor. He said take 25mg of Benadryl tonight and Zyrtec in the morning, "moisturize like it's a job" and call his office in the morning.

July 6, 2025
A MyEndometrialCancerTeam Member

Feeling much better, thanks, and yes my oncologist approved 25 mg of Benadryl at night and a Zyrtec in the morning. Benadryl only as needed but for now the Zyrtec is an every day thing.

July 21, 2025
myEndometrialCancerTeam

First and most importantly - contact your cancer care team right away about your rash. They need to monitor your side effects closely and can provide specific medications and treatments that are safe with your chemotherapy regimen. They may need to adjust your treatment plan or prescribe appropriate medications. While Show Full Answer

First and most importantly - contact your cancer care team right away about your rash. They need to monitor your side effects closely and can provide specific medications and treatments that are safe with your chemotherapy regimen. They may need to adjust your treatment plan or prescribe appropriate medications. While waiting to speak with your care team, here are some general comfort measures that may help:

- Continue using fragrance-free moisturizers
- Try cool compresses on affected areas (but check with your doctor first)
- Wear loose, soft clothing that won't irritate your skin
- Avoid hot showers/baths that could further dry out or irritate your skin
- Stay hydrated by drinking plenty of water

Don't take any medications, including over-the-counter options like Benadryl, without first checking with your healthcare team, as they need to ensure it won't interact with your chemotherapy.

July 6, 2025
A MyEndometrialCancerTeam Member

Did your oncologist say you could take Benadryl? I know the predrugs I had included IV Benadryl before the chemotherapy. Hope you are feeling better !!🤗

July 21, 2025
A MyEndometrialCancerTeam Member

Doctor ended up providing a steroid cream which seemed to calm it down a bit. I also switched moisturizers to one that was recommended specifically for cancer patients and it has been very helpful. Use it a few times a day. Hoping now that I have a routine in place with it and the steroid cream as a back up that I will not suffer so much this round!

July 19, 2025

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