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Real members of MyEndometrialCancerTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Has anyone had the Signatera blood test?

A MyEndometrialCancerTeam Member asked a question 💭

Hi, I'm currently waiting for my Signatera blood test. For those of you who have had it, what are your thoughts? Did you have it after your diagnosis, and do you still get tested? Any insight would be helpful!

September 23, 2025
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A MyEndometrialCancerTeam Member

Hi Heather,
I have had 2 rounds so far, June after full hysterectomy came back 0.10 and recently did one during last chemo on 11/3 came back 0.18. Also do the CA 125 started at 12 then down to 7 and after 2nd chemo down to 3, 5th chemo up to 4 and 6th up to 5.5 of course it set off my new found anxiety but my doctor said CT scan clear and radiation was just beginning so let’s keep an eye on it. I have blood work next Sunday then Jemperli immunotherapy infusion on 1/5. Trying to stay calm and positive.

What has your experience been?

December 28, 2025
A MyEndometrialCancerTeam Member

It’s a valuable tool for the dr

September 28, 2025
A MyEndometrialCancerTeam Member

I had my second one done 3 months ago. My first was negative. I also get Ca125 and PET scans and CT with Contrast…

September 23, 2025
myEndometrialCancerTeam

While blood tests can be helpful tools in monitoring endometrial cancer, they are typically used alongside other diagnostic methods. The most common blood test used for endometrial cancer is the CA-125 test, which can indicate if cancer has spread but isn't used for initial diagnosis.

Blood tests may also be used to
• Show Full Answer

While blood tests can be helpful tools in monitoring endometrial cancer, they are typically used alongside other diagnostic methods. The most common blood test used for endometrial cancer is the CA-125 test, which can indicate if cancer has spread but isn't used for initial diagnosis.

Blood tests may also be used to:
• Check kidney and liver function to help guide treatment
• Perform a complete blood count (CBC) to check for anemia from bleeding
• Look for specific proteins and genetic mutations
• Determine if certain treatments like immunotherapy might be effective Biomarker testing through blood work can provide valuable information about potential inherited mutations and help determine the most effective treatment options for your specific case. It's recommended to discuss with your healthcare team about which blood tests are most appropriate for monitoring your condition and how frequently they should be performed.

September 23, 2025

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