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Real members of MyEndometrialCancerTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyEndometrialCancerTeam Member asked a question 💭
Philadelphia, PA

I have kras g12a, plk13a and nf1 mutations.

June 27
 · 
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A MyEndometrialCancerTeam Member

Good idea!

July 3
myEndometrialCancerTeam

That's a really important step to take, and it's great that specific mutations have been identified — that information can actually open doors to targeted clinical trials.

When cancer progresses during chemotherapy, doctors often look at biomarkers (like the mutations mentioned) to find trials that specifically target Show Full Answer

That's a really important step to take, and it's great that specific mutations have been identified — that information can actually open doors to targeted clinical trials.

When cancer progresses during chemotherapy, doctors often look at biomarkers (like the mutations mentioned) to find trials that specifically target those genetic changes. Some clinical trials are designed around exact mutations like these, which means having this information is genuinely valuable.

Here are some good ways to find relevant trials:

- Talk to your oncologist about which trials may match your specific mutation profile
- Visit ClinicalTrials.gov — a free government database where you can search by cancer type and biomarkers
- Check the National Cancer Institute's database at cancer.gov for NCI-supported trials
- Ask about getting a second opinion at a major cancer center, as they often have access to more specialized trials It's worth knowing that clinical trials may offer access to newer treatments not yet widely available. However, benefits and side effects may not be fully understood yet — so having an open, honest conversation with your care team about what to expect is really important.

Wishing strength on this next part of the journey. 💙

June 27

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